Comedy Shows in La Mesa, CA

• Nate Bargatze – Big Dumb Eyes World Tour

  Thursday, July 16, 2026 · 7:00 PM

  Pechanga Arena San Diego, 3500 Sports Arena Blvd, San Diego, CA

  See tickets

• Weird Al" Yankovic: Bigger & Weirder Tour

  Wednesday, September 16, 2026 · 7:00 PM

  The Rady Shell at Jacobs Park, 200 Marina Park Way, San Diego, CA

  See tickets

• Uncensored Improv

  Friday, July 17, 2026 · 9:45 PM

  2590 Truxtun Rd, Studio 200 (aka Bldg 176 / Dorothea Laub Music & Arts Center), CA

  $15–$17

• All Hands On Deck

  Saturday, July 18, 2026 · 7:00 PM

  2590 Truxtun Rd, Studio 200 (aka Bldg 176 / Dorothea Laub Music & Arts Center), CA

  $15–$17

• Improv vs Standup

  Saturday, July 18, 2026 · 8:30 PM

  2590 Truxtun Rd, Studio 200, CA

  $15–$17

• Perritos Only Presents: That's Not Me Comedy

  Saturday, July 25, 2026 · 8:00 PM

  The Magnolia, 210 E Main Street, El Cajon, CA

  See tickets

• Kevin Smith

  Saturday, July 25, 2026 · 9:00 PM

  The American Comedy Co., 818 B 6th Ave, San Diego, CA 92101, San Diego, CA

  See tickets

• Murray & Peter Present The Marvelous Miss Gender Tour

  Saturday, August 1, 2026 · 7:00 PM

  The Observatory North Park, 2891 University Ave, San Diego, CA

  See tickets

• SmackDown

  Sunday, August 2, 2026 · 8:30 PM

  2590 Truxtun Rd, Studio 200 (aka Bldg 176 / Dorothea Laub Music & Arts Center), CA

  See tickets

• Let Me Have It! An All-Femme Improv Extravaganza

  Friday, August 14, 2026 · 9:45 PM

  2590 Truxtun Rd, Studio 200 (aka Bldg 176 / Dorothea Laub Music & Arts Center), CA

  $15–$17

• Leslie Liao

  Saturday, August 15, 2026 · 7:00 PM

  The American Comedy Co., 818 B 6th Ave, San Diego, CA 92101, San Diego, CA

  See tickets

• Little Shop of Horrors ft. Ellen Greene

  Saturday, August 15, 2026 · 7:00 PM

  Balboa Theatre, 868 Fourth Avenue, San Diego, CA

  $48

• Brad Williams: Tall Tales Tour

  Friday, August 28, 2026 · 7:30 PM

  Humphreys Concerts By the Bay, 2241 Shelter Island Dr., San Diego, CA

  $74

• Dan and Phil: Hard Launch World Tour

  Tuesday, September 8, 2026 · 7:30 PM

  Balboa Theatre, 868 Fourth Avenue, San Diego, CA

  See tickets

• Kathy Griffin: New Face, New Tour

  Sunday, September 13, 2026 · 6:00 PM

  The Magnolia, 210 E Main Street, El Cajon, CA

  See tickets

• FOOS GONE WILD Tour

  Thursday, September 17, 2026 · 7:00 PM

  House of Blues San Diego, 1055 5th Avenue, San Diego, CA

  See tickets

• Killers of Kill Tony

  Friday, September 18, 2026 · 7:00 PM

  San Diego Civic Theatre, 3rd & B St., San Diego, CA

  See tickets

• Chelsea Handler: The High and Mighty Tour

  Saturday, September 19, 2026 · 8:00 PM

  Balboa Theatre, 868 Fourth Avenue, San Diego, CA

  $73

• Brincos Dieras - El Desmadre Continua Tour

  Sunday, September 27, 2026 · 7:00 PM

  Balboa Theatre, 868 Fourth Avenue, San Diego, CA

  See tickets

• Oh, Mary! Touring

  Tuesday, September 29, 2026 · 7:00 PM

  San Diego Civic Theatre, 3rd & B St., San Diego, CA

  See tickets

• Jessica Kirson

  Saturday, October 3, 2026 · 6:00 PM

  The Observatory North Park, 2891 University Ave, San Diego, CA

  See tickets

• Adam Ray: WHO IS ME Tour

  Saturday, October 3, 2026 · 7:00 PM

  Balboa Theatre, 868 Fourth Avenue, San Diego, CA

  See tickets

• Bassem Youssef: The Belly of the Beast Tour

  Friday, October 9, 2026 · 7:30 PM

  Balboa Theatre, 868 Fourth Avenue, San Diego, CA

  See tickets

• Jonathan Van Ness: Hot & Healed Comedy Tour

  Saturday, October 10, 2026 · 8:00 PM

  Balboa Theatre, 868 Fourth Avenue, San Diego, CA

  See tickets

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