Nightlife Events in La Mesa, CA — This Weekend

Discover nightlife events this weekend in La Mesa, CA on VibeHawk. Browse upcoming events with dates, venues, and ticket prices, then tap any listing for details and tickets.

• Wine Vault Bistro: Journeyman Winemaker Dinner with Pete and Cathy Seghesio

  Saturday, July 18, 2026 · All day

  3731 India St., San Diego, California, CA

  See tickets

• Uncle Lazer

  Saturday, July 18, 2026 · 7:00 PM

  The American Comedy Co., 818 B 6th Ave, San Diego, CA 92101, San Diego, CA

  See tickets

• BRICK²

  Saturday, July 18, 2026 · 9:00 PM

  3845 Fifth Avenue, San Diego, CA 92103, San Diego, CA

  $23.18–$39.19

• Birch After Hours

  Sunday, July 19, 2026 · All day

  Birch Aquarium at Scripps, CA

  $19.95

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